4.83 | 41 reviews

Cycle Bestie

Biohack your cycle with targeted support for cramps, energy, bloating, and hormone balance—all month long.

Description
  • BIOHACK YOUR CYCLE: This hormone balance supplement was made to help you feel more comfortable throughout your cycle. Ingredients like ginger extract and magnesium glycinate may help with cramps

  • PHASE SPECIFIC SUPPLEMENTS: Our capsules help nurture your body each step of your cycle with four different phase packs. Each unique pack uses scientifically backed ingredients for hormone balance

  • HELP MAINTAIN ENERGY LEVELS: The PMS support supplements from Phase I (Winter) and Phase II (Spring) focus on promoting energy levels and helping regulate your cycle with ginger extract and vitamin D3

  • SUPPORT RELAXATION: Phase III (Summer) and Phase IV (Fall) promote a calm mindset and help with bloating using our hero ingredient L-Ergothioneine, which is a naturally occurring amino acid
What to expect

What to Expect:

First Hour: You may feel initial relief from cramps and discomfort as ingredients like Ginger Extract and Black Cohosh work to soothe your body during your cycle.

After 1-2 Weeks: Experience improved energy levels, mood stability, and fewer PMS symptoms, thanks to hormonal-balancing ingredients like Magnesium Glycinate and Vitamin B6.

After 1-2 Months: Enjoy more regular, pain-free cycles, clearer skin, and less bloating as DIM, Chasteberry, and CoQ10 regulate your hormones.


Ready to Finally Stop Dreading Your Period?

Cycle Bestie is your Swiss Army Knife for a smooth, balanced cycle – one capsule a day is all you need! Whether you’re struggling with PMS, hormonal acne, or irregular periods, Cycle Bestie helps you regain control and thrive through every phase of your cycle. Support your hormones naturally and feel your best, every day of the month.

Supplement Facts

Key Players in This Formula:

Ergothioneine: A powerful antioxidant that protects your cells from oxidative stress and promotes better skin health.
DIM (Diindolylmethane): Helps balance estrogen levels, reducing PMS symptoms like mood swings and hormonal acne.
Magnesium Glycinate: Reduces cramps and promotes calm during PMS while supporting energy levels throughout your cycle.
Chasteberry: Balances hormones to reduce bloating, irritability, and PMS discomfort.
CoQ10 Ubiquinone: Supports egg health and fertility while boosting energy levels.
Vitamin B6: Helps regulate mood, easing irritability and fatigue during PMS.
Black Cohosh: Eases menstrual discomfort, supporting smoother, less painful cycles.

Quality You Can Trust:
• Formulated with clinically proven ingredients
• No synthetic hormones or harsh chemicals
• Non-GMO
• Vegan-friendly
• Gluten-free
• Third-party tested
• Made in the USA

Full Ingredient List:

The Menstruation Phase, a time of release and renewal for your body. While it can come with its own set of challenges, we’ve meticulously crafted a blend to support you through every moment, making your period a more comfortable and empowering experience.

Iron Bisglycinate (18 mg): Iron Bisglycinate replenishes lost iron from menstruation, ensuring gentle stomach absorption to maintain energy and balance.

Uva Ursi (20% arbutins, 250mg): Uva Ursi manages UTI risk and bloating during menstruation, promoting a smoother week.

Black Cohosh (20mg, 2.5% triterpene glycosides): Black Cohosh regulates hormone fluctuations, easing menstrual symptoms for a more comfortable experience.

Ginger Extract (5% gingerols, 250mg): Ginger Extract provides natural, effective relief for menstrual cramps, alleviating pain without the use of traditional painkillers.

L-Ergothioneine (MitoPrime, 5mg): L-Ergothioneine acts as an antioxidant guard during your period, maintaining cellular peace and balance for a stress-free renewal process.


Follicular Phase, where your body gears up for the main event: ovulation. It’s a time of preparation and potential, and we’ve got just the mix to support you through this crucial stage. Here's what makes our Follicular blend a game-changer for your cycle.

  • Zinc Picolinate (15 mg): Zinc Picolinate prepares your body for ovulation and boosts fertility in an easily absorbable form.
  • Vitamin D3 (1000 IU): Vitamin D3 strengthens bones and may help regulate your menstrual cycle.
  • Folate 668g mcg (400mcg Folic acid): Folate prepares your body for potential pregnancy by ensuring you have enough of this essential nutrient.
  • DIM (Diindolylmethane, 400 mg): DIM helps balance estrogen levels, addressing issues like acne and mood swings.
  • CoQ10 Ubiquinone (100mg): CoQ10 Ubiquinone supports egg health, acting like a personal trainer for your eggs.
  • L-Ergothioneine (MitoPrime, 5mg): L-Ergothioneine protects cells from oxidative stress, supporting follicle development.


Ovulation Phase, the spotlight moment in your cycle where fertility peaks and your body performs one of its most incredible acts: releasing an egg ready for fertilization. Your body deserves nothing but the best support. That's where Ovulation blend steps in, packed with everything you need to support this critical process.

  • Selenium Glycinate (55 mcg): Selenium Gycinate supports ovulation and is easily absorbed by the body.
  • Nettle Extract (standardized for 5% phytosterols, 300 mg): Nettle Extract calms inflammation and aids the liver in clearing hormonal clutter for smooth ovulation.
  • NAC (N-acetyl-cysteine, 150mg): NAC boosts ovulation rates, particularly beneficial for those with PCOS or irregular cycles.
  • Dihydroberberine (GlucoVantage, 150mg): Dihydroberberine regulates insulin levels, supporting regular ovulation and proving to be more effective than berberine and cinnamon.
  • L-Ergothioneine (MitoPrime, 5mg): L-Ergothioneine protects eggs and surrounding cells from oxidative stress during ovulation, safeguarding your fertility.


Luteal Phase, the final stretch before your menstrual cycle begins anew. It's a time when your body is winding down from the ovulation high and preparing for what's next, often bringing along the dreaded PMS symptoms. We've formulated the perfect blend to support you through this.

  • Vitamin B6 (pyridoxine, 50 mg): Vitamin B6 reduces PMS symptoms for a more balanced mood.
  • Magnesium Glycinate (300 mg): Magnesium Glycinate eases PMS symptoms, providing a calming effect.
  • Chasteberry (Vitex, 0.5% agnuside, 200 mg): Chasteberry naturally relieves PMS symptoms by balancing hormones.
  • RhodioPrime Rhodiola (standardized for 6% salidrosides, 200 mg): Rhodiola boosts energy and mental focus, reducing fatigue and foggy feelings.
  • Saffron (standardized for saffranals, 88mg): Saffron uplifts mood, particularly helpful for PMS-related depression.
  • L-Ergothioneine (MitoPrime, 5mg): L-Ergothioneine protects cells from oxidative stress and inflammation during the transition into menstruation.
How To Take

Recommended Use: Choose the blend that corresponds with the current phase of your cycle, then take our supplement daily with food. For optimal results, take one capsule every day at the same time

Safety Guidelines: Consult your healthcare provider if pregnant, nursing, or taking medications. Do not exceed the recommended daily dose. Discontinue use if any adverse reactions occur.

Answers to all your questions

Cycle Bestie supports hormonal balance by providing tailored nutritional support throughout each phase of your menstrual cycle, addressing PMS, cramps, bloating, and irregular periods.

You can expect initial relief within 1-2 weeks, with more noticeable improvements in mood, energy, and hormonal balance within 1-2 months of consistent use.

Yes, ingredients like Magnesium Glycinate and Black Cohosh help reduce cramps, while Chasteberry and Vitamin B6 address PMS symptoms.

Yes, Cycle Bestie contains ingredients like NAC and DIM, which are beneficial for women with PCOS and irregular cycles by supporting hormone balance and regular ovulation.

Cycle Bestie is formulated for long-term use. If you don’t see results after consistent use, consult your healthcare provider, as additional factors may be influencing your hormonal health.

While Cycle Bestie is generally safe, consult your healthcare provider before combining it with other supplements or medications, especially those affecting hormones.

Yes, Cycle Bestie is vegan-friendly, gluten-free, and free from common allergens.

Simply follow the cycle-specific blister packs included in your order. Each pack is designed for a different phase of your menstrual cycle.

If you don't have a regular period or are transitioning off birth control, start Cycle Bestie with the Follicular Phase pack and follow the sequence from there.

Absolutely! Cycle Bestie is designed to support natural hormone balance, whether or not you are on birth control.

What we say ‘No’ to

Prohibited ingredients for large screens
Prohibited ingredients for small screens

Our ingredients

At Biohacking Bestie, we're obsessed with sourcing the finest, science-backed ingredients that deliver exceptional results. Here are some of the superstar ingredients we absolutely adore!

Apple Cider Vinegar

Bladderwrack

Buchu

Burdock

Butternut

Cascara Sagrada

Catnip

Chickweed

Cinnamon

Citrus Aurantium

Cloves

Coleus Forskohlii

Corn Silk

Dandelion

Echinacea Purpurea

Fennel

Ginger Root

Ginkgo Biloba

Customer Reviews

Based on 41 reviews
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J
Jenn
Menstrual Migraines Lessened

I struggled with debilitating menstrual migraines for years. After taking cycle bestie my once 5-7 day migraine turned into one day of a manageable headache. This is a miracle worker! Prior to this I had tried everything including many many supplements, changing my diet, HRT, and more and nothing helped my migraines like this. I have recommended to many friends!

A
Amelia
Warning: Inconsistent Supply Makes Cycle Bestie Risky

I wanted to leave honest feedback about Cycle Bestie. The concept behind this product is great—using supplements that align with different phases of the cycle makes sense, and many of the ingredients do help with balance and regulation. However, the execution has been extremely disappointing.

The biggest issue is consistency. You cannot take something that directly affects hormones, get your body adjusted to it, and then suddenly be forced to stop because it’s out of stock. That kind of on-and-off pattern is terrible for the body, especially for anyone who has been on it long enough to feel the effects. From someone who works in the medical field, this is not just inconvenient, it’s irresponsible.

Being out of stock means people are essentially forced to “withdraw” from something their body has adjusted to, and then start the whole process over again when it comes back. That’s far more damaging in the long run than not being on it at all. If you’re going to sell a product that influences hormones, it is absolutely critical that it be available consistently.

Watching the company’s social media makes it even more frustrating—while the owner is posting vacations, customers are left hanging without access to something their body has become dependent on. This is not just poor planning, it’s a major red flag for a business model that involves something as sensitive as hormone regulation.

If Cycle Bestie wants to be taken seriously in the wellness space, they need to prioritize keeping this product in stock at all times. Otherwise, it ends up doing more harm than good.

Hi there,

Thank you so much for your thoughtful feedback. I want to clarify a couple of things that may help put Cycle Bestie into perspective.

First, we actually recommend pausing Cycle Bestie every six months. The goal is never to get your body dependent on it, but instead to follow a more holistic approach. It is very different from the typical Western model of “stay on a product forever.” Hormones are dynamic, and it’s important to give the body breaks rather than keep it in constant adaptation mode. The goal is for your hormones to thrive without our product, not be dependent on it.

Second, we are 100% family-owned and self-funded. That means we don’t have big investors overproducing for us—we do our best to forecast demand, but sometimes when a post goes viral and the product hits an algorithm, we sell out faster than expected. While this is never our intention, it’s also a reflection of being a small, authentic company rather than a mass-production machine.

Lastly, regarding social media, I want to be transparent: I’m eight months pregnant right now and stepping into maternity leave with my own “Cycle Bestie baby.” If me not working late into pregnancy or early motherhood makes someone lose trust in our company, I’d argue it should be the opposite. Supporting women in their wellness journey means also honoring motherhood, rest, and balance behind the scenes.

We take all feedback seriously and are constantly improving our supply chain, but I hope this gives you a clearer picture of our philosophy and why things may look different compared to larger companies.

With gratitude,
Aggie

Z
Zoë Hasert
Love it; helps me so much with my PCOS struggles!

As someone who’ve had PCOS her whole life, and had even been on medication to get her cycle back after miscarriage, Cycle Bestie is working wonders! I’m currently off meds, on Cycle Bestie and havehad my own natural cycles! Somewhat longer than 28 days, but oh well ;) Really happy and totally recommend!

O
Olga
Great product

Strongly recommend.

A
Alexandra M
Seeing a difference & only 1 month in!

When it comes to PMS supplements, I feel like I've tried them all. During my luteal phase, I feel like I gain about 10 pounds, I am so bloated that not only do my clothes not fit around that time of the month but so uncomfortable. I stumbled across cycle bestie and even though I'm still in my first month pack, I'm in my luteal phase and already see a huge difference in bloating compared to how it normally is during this phase. I feel like cycle bestie is working with me and I'm excited to see the results of month 2&3!!