4.93 | 44 reviews

Cycle Bestie

She’s finally back, better than ever! Cycle Bestie is officially available with an upgraded formula designed to support you through every phase of your cycle. From cramps to cravings, low energy to hormonal acne, we’ve got you covered.

 

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Description

Daily Cycle-Synced Hormone Support
New & Improved Formula

Struggling with bloating, PMS, low energy, mood swings, or feeling disconnected from your body throughout the month?

Cycle Bestie is a 4-phase, cycle-synced supplement system designed to support your body differently in each phase of your menstrual cycle, because your hormones don’t need the same support every day.

Instead of a one-size-fits-all hormone supplement, Cycle Bestie gives your body what it needs, when it needs it, helping you feel more balanced, energized, and in tune with your cycle.

The new and improved Cycle Bestie features upgraded ingredients, better bioavailability, and more targeted phase support to help reduce common cycle-related symptoms while supporting long-term hormone balance.

Get ready to feel more supported through every phase, physically, mentally, and emotionally.

Why You’ll Love Cycle Bestie

Phase-Specific Hormone Support
Four unique formulas designed to align with each phase of your cycle.

Eases PMS, Cramps & Bloating
Supports inflammation pathways, progesterone balance, and digestion.

Boosts Energy & Mood Throughout the Month
Supports mitochondrial health, nervous system balance, and blood sugar regulation for steadier energy.


Supports Skin, Mood & Stress Resilience
Targets root causes like hormone metabolism, stress response, and nutrient depletion.


Perfect for You If You…

• Experience PMS, cramps, bloating, mood swings, or cycle-related fatigue
• Feel like your energy and emotions change week to week
• Want hormone support that works with your cycle
• Are tired of generic, one-formula hormone supplements
• Prefer clean, thoughtfully formulated supplements

What’s New & Improved in Each Phase

Phase 1: Menstrual

Focused on recovery, comfort, and replenishment

  • Increased Ginger Extract to better ease cramps, inflammation, and bloating
  • Continued gentle Iron support to replenish levels after blood loss
  • Maintained Uva Ursi for urinary tract and bladder support
  • Included L-Ergothioneine (MitoPrime®) for cellular and mitochondrial recovery


Phase 2: Follicular

Focused on renewal, energy, and hormone metabolism

  • Upgraded Folate to methylated L-5-MTHF for improved absorption
  • Standardized Vitamin D3 sourcing to support hormone signaling and ovarian function
  • Continued Zinc to support ovulation and hormone communication
  • Maintained DIM for healthy estrogen metabolism
  • Included CoQ10 and L-Ergothioneine (MitoPrime®) for cellular energy and follicle protection


Phase 3: Ovulatory

Focused on balance, blood sugar, and cellular protection

  • Maintained Dihydroberberine (GlucoVantage®) for blood sugar and insulin balance
  • Continued NAC to support detox and antioxidant pathways
  • Included Selenium and Nettle Extract to support hormone balance and inflammation control
  • Preserved L-Ergothioneine (MitoPrime®) for mitochondrial protection during peak activity


Phase 4: Luteal

Focused on mood, stress resilience, and PMS support

  • Upgraded Vitamin B6 to active P5P for stronger PMS and progesterone support
  • Reduced Magnesium Glycinate to improve tolerance while supporting relaxation and sleep
  • Added Phosphorus for cellular energy and mineral balance
  • Replaced rhodiola with SalidroPure® for consistent stress resilience
  • Improved Saffron Extract standardization for reliable mood support
  • Continued Chasteberry (Vitex) for progesterone signaling
  • Included L-Ergothioneine (MitoPrime®) for nervous system protection
What to expect

First Cycle
Subtle but meaningful shifts like less bloating, improved energy, or better mood during challenging phases.


After 2–3 Cycles
Reduced PMS symptoms, clearer skin, steadier energy, and improved cycle predictability.


With Continued Use
Long-term support for hormone balance, stress resilience, and a healthier relationship with your cycle.

Quality You Can Trust
No Fillers
No Artificial Colors, Flavors, or Preservatives
Gluten-Free
Non-GMO
Third-Party Tested
Manufactured in a GMP-Certified Facility

How Cycle Bestie Works

How Cycle Bestie Works

Cycle Bestie includes four phase-specific formulas, each supporting your body’s natural hormonal rhythm:

Menstrual Phase: Replenishment, comfort, and recovery
Follicular Phase: Energy, renewal, and hormone metabolism
Ovulatory Phase: Balance, blood sugar support, and cellular protection
Luteal Phase: Mood support, stress resilience, and nervous system calm


Each phase builds on the last to support a smoother, more predictable cycle over time.

Supplement Facts

PHASE 1: MENSTRUAL

Serving Size: 1 Capsule
Servings Per Container: 5


Supplement Facts (Amount Per Capsule)

  • Iron (as Ferrous Bisglycinate Chelate) – 18 mg (100% DV)

  • Ginger Root Extract (Zingiber officinale) (Std. 5% Gingerols) – 300 mg †

  • Uva Ursi Extract (Arctostaphylos uva-ursi) (Leaf) (Std. 20% Arbutins) – 250 mg †

  • MitoPrime® L-Ergothioneine – 5 mg †

Other Ingredients:
Vegetable Capsule, Rice Flour, Maltodextrin, Citric Acid, Silica


PHASE 2: FOLLICULAR

Serving Size: 1 Capsule
Servings Per Container: 7


Supplement Facts (Amount Per Capsule)

  • Vitamin D3 (from Lichen) – 25 mcg (1000 IU) (125% DV)

  • Folate (as L-5-Methyltetrahydrofolate Calcium) – 400 mcg DFE (100% DV)

  • Zinc (from Zinc Picolinate) – 15 mg (136% DV)

  • DIM (Diindolylmethane) – 400 mg †

  • Coenzyme Q10 (CoQ10) – 100 mg †

  • MitoPrime® L-Ergothioneine – 5 mg †

Other Ingredients:
Vegetable Capsule, Maltodextrin


PHASE 3: OVULATORY

Serving Size: 1 Capsule
Servings Per Container: 3


Supplement Facts (Amount Per Capsule)

  • Selenium (as Selenium Glycinate) – 55 mcg (100% DV)

  • Nettle Extract (Urtica dioica) (Leaf) (Std. 5% Phytosterols) – 300 mg †

  • N-Acetyl-L-Cysteine (NAC) – 150 mg †

  • GlucoVantage® Dihydroberberine – 150 mg †

  • MitoPrime® L-Ergothioneine – 5 mg †

Other Ingredients:
Vegetable Capsule, Rice Flour, Maltodextrin


PHASE 4: LUTEAL

Serving Size: 1 Capsule
Servings Per Container: 13


Supplement Facts (Amount Per Capsule)

  • Vitamin B6 (as Pyridoxal-5-Phosphate) – 50 mg (2941% DV)

  • Phosphorus – 26 mg (2% DV)

  • Magnesium (as Magnesium Glycinate) – 90 mg (21% DV)

  • Chasteberry Extract (Vitex agnus-castus) (Fruit) (Std. 0.5% Agnuside) – 200 mg †

  • Saffron Extract (Crocus sativus) (Stigma) (Std. 0.3% Safranal) – 88 mg †

  • SalidroPure® (Std. 98% Salidrosides) – 30 mg †

  • MitoPrime® L-Ergothioneine – 5 mg †

Other Ingredients:
Vegetable Capsule, Microcrystalline Cellulose, Maltodextrin

How to take

Suggested Use:

Take 1 capsule daily, following the cycle-specific blister packs to align with each phase of your menstrual cycle.

Safety Guidelines: Consult your healthcare provider if pregnant, nursing, or taking medications. Do not exceed the recommended daily dose. Discontinue use if any adverse reactions occur.

Answers to all your questions

Cycle Bestie supports hormonal balance by providing tailored nutritional support throughout each phase of your menstrual cycle, addressing PMS, cramps, bloating, and irregular periods.

You can expect initial relief within 1-2 weeks, with more noticeable improvements in mood, energy, and hormonal balance within 1-2 months of consistent use.

Yes, ingredients like Magnesium Glycinate and Black Cohosh help reduce cramps, while Chasteberry and Vitamin B6 address PMS symptoms.

Yes, Cycle Bestie contains ingredients like NAC and DIM, which are beneficial for women with PCOS and irregular cycles by supporting hormone balance and regular ovulation.

Cycle Bestie is formulated for long-term use. If you don’t see results after consistent use, consult your healthcare provider, as additional factors may be influencing your hormonal health.

While Cycle Bestie is generally safe, consult your healthcare provider before combining it with other supplements or medications, especially those affecting hormones.

Yes, Cycle Bestie is vegan-friendly, gluten-free, and free from common allergens.

Simply follow the cycle-specific blister packs included in your order. Each pack is designed for a different phase of your menstrual cycle.

If you don't have a regular period or are transitioning off birth control, start Cycle Bestie with the Follicular Phase pack and follow the sequence from there.

Absolutely! Cycle Bestie is designed to support natural hormone balance, whether or not you are on birth control.

What we say ‘No’ to

Prohibited ingredients for large screens
Prohibited ingredients for small screens

Our ingredients

At Biohacking Bestie, we're obsessed with sourcing the finest, science-backed ingredients that deliver exceptional results. Here are some of the superstar ingredients we absolutely adore!

Apple Cider Vinegar

Bladderwrack

Buchu

Burdock

Butternut

Cascara Sagrada

Catnip

Chickweed

Cinnamon

Citrus Aurantium

Cloves

Coleus Forskohlii

Corn Silk

Dandelion

Echinacea Purpurea

Fennel

Ginger Root

Ginkgo Biloba